| Lotemax gel (U.S.N.L.M.) | |
|---|---|
| Dosing | 1 or 2 drops applied qid beginning 24 hours after surgery and for following 2 weeks. tid dosing used in the 0.38% version due to smaller particle size and better penetration. |
| Chem Specs | loteprednol etabonate 0.38% and 0.5% |
| Quantities | 0.38% gel in 5m bottle and 0.5% gel in 10ml bottle. |
| Cost | $290 (0.38%), $80.42 (0.5%) |
| Class | Ester based "soft" steroid. |
| Action | Anti-inflammatory |
| Indications | Post-operative inflammation and pain. |
| Gel often used for inflammatory dry eye, uveitis, inflamed pinguecula and pterygia. | |
| Prolonged use may cause glaucoma, cataracts, bacterial and fungal overgrowth. | |
| Contraindications | Most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis, vaccinia, and varicella, mycobacterial and fungal disease. Hypersensitivity to any of the ingredients of this preparation and to other corticosteroids. |
| Pediatric use | Safety and effectiveness in pediatric patients has been established. |
| Pregnancy | Teratogenic in rabbits at 1.2x the normal human dose. |
| Contact lenses should not be used during course of therapy. Gel contains moisturizers glycerin and propylene glycol and polycarbophil mucoadhesive polymer. Gel comes in a bottle with BAK (0.003%). Akorn gel generic FDA approved February 2021. |